منابع مشابه
Sympathetic activation in chronic renal failure.
The potential involvement of sympathetic overactivity has been neglected in this population despite accumulating experimental and clinical evidence suggesting a crucial role of sympathetic activation for both progression of renal failure and the high rate of cardiovascular events in patients with chronic kidney disease. The contribution of sympathetic neural mechanisms to the occurrence of card...
متن کاملChronic sympathetic activation: consequence and cause of age-associated obesity?
Primary aging in adult humans is associated with a progressive, tonic activation of the peripheral sympathetic nervous system (SNS). The purpose of this SNS activation and its physiological impact are, however, unknown. We hypothesize that the chronic stimulation of the SNS with aging is driven in part by a progressive accumulation of body fat. This "error" is sensed by the central nervous syst...
متن کاملSympathetic activation in chronic kidney disease: out of the shadow.
Chronic kidney disease (CKD) is a global and growing health problem. In the United States alone, an estimated 20 million people are affected by CKD, equating to 13% of the adult population.1 While carrying an increased risk for the development of end-stage renal disease (ESRD), the major threat to patients with CKD is the associated morbidity and mortality from cardiovascular causes, which is u...
متن کاملSympathetic activation by sildenafil.
BACKGROUND Sildenafil citrate is an effective and widely prescribed therapy for erectile dysfunction. Little is known about the effects of sildenafil on neural control of the circulation or about the effects of sildenafil on neurocirculatory stress responses. METHODS AND RESULTS We studied 14 normal volunteers (age 32+/-7 years) who were randomized in a double-blind crossover fashion to recei...
متن کاملSympathetic Nervous Activation and Failure
Background Although heart rate variability (HRV) at 0.1 Hz has been proposed as a noninvasive clinical measure of cardiac sympathetic nerve firing, this premise has not been sufficiently validated by comparison with techniques such as microneurography and the measurement of norepinephrine spillover from the heart that more directly reflect presynaptic sympathetic activity. Methods and Results W...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2002
ISSN: 0025-6196
DOI: 10.4065/77.7.734-a